Use of promethazine and codeine mix will not be suggested in little ones younger than 6 a long time of age for syrup or in youngsters younger than twelve decades of age for oral Option, because of the amplified chance of respiratory melancholy.
Usually do not share promethazine/phenylephrine/codeine with other people, whether or not they have the identical ailment when you. It may well hurt them.
Moms who are ultra-quick metabolizers of codeine achieve bigger-than-anticipated serum amounts of morphine, likely bringing about bigger levels of morphine in breast milk that can be risky for their breastfed infants.
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Acceptable reports done so far have not demonstrated geriatric-particular complications that will limit the usefulness of promethazine and codeine blend during the aged.
In situations of overdose, You may use naloxone to briefly reverse the results of codeine and also other opioids. It has to be provided as soon as possible, not more than twenty to thirty minutes following the codeine has become taken.
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We urge clients and health and fitness treatment pros to report Unintended effects involving codeine-and tramadol- containing medicines to your FDA MedWatch software, applying the knowledge from the “Get in touch with FDA” box at The underside from the page.
常見之不良反應有：瘙癢、噁心、嘔吐、昏睡、口乾、瞳孔縮小、姿態性低血壓（orthostatic hypotension）、小便不暢、便秘。
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Nursing moms having codeine can also have larger morphine levels of their breast milk Should they be ultra-fast metabolizers. These greater levels of morphine in breast milk might bring on lifestyle-threatening or fatal Unwanted side effects in nursing toddlers. Instruct nursing mothers to Look ahead to indications of morphine toxicity in their infants which include increased sleepiness (more than standard), problems breastfeeding, respiratory complications, or limpness.
Codeine: Dosage of codeine Shouldn't be Improved if cough fails to reply; an unresponsive cough really should be reevaluated in 5 times or quicker for attainable fundamental pathology, more info for instance foreign overall body or decrease respiratory tract disorder. Codeine may possibly lead to or aggravate constipation.
In women with usual codeine metabolism, the level of codeine secreted into breast milk is lower and dose-dependent.